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CareDx and Miromatrix Announce Exclusive Partnership to Advance Research Using Bioengineered Organs for Human Transplantation

April 5, 2023

CareDx Exclusive Provider of dd-cfDNA Testing Services for Use in Miromatrix Clinical Trials

Companies at Forefront of Alternative Organ Supply Research to Address Organ Shortage

BRISBANE, Calif. and EDEN PRAIRIE, Minn., April 05, 2023 (GLOBE NEWSWIRE) -- CareDx, Inc. (Nasdaq: CDNA) and Miromatrix Medical Inc. (“Miromatrix”) (Nasdaq: MIRO) -- today announced an exclusive partnership aimed at advancing the next wave of innovation using fully transplantable human bioengineered organs.

CareDx will develop an innovative testing solution for Miromatrix to use in pre-clinical animal models and will be the exclusive provider of donor-derived cell-free DNA (dd-cfDNA) testing services for use in human clinical studies to non-invasively assess acute allograft rejection in Miromatrix’s pipeline of human bioengineered organs.

“We are committed to being at the forefront of driving the next wave of innovation to address the organ supply shortage in transplantation through this collaboration with Miromatrix. We hope one day that bioengineered organs will become a reality for the thousands of patients waiting for a life-saving organ,” said Reg Seeto, CEO and President of CareDx. “We are proud to partner with Miromatrix, a leader at the forefront of human bioengineered organ development as they apply our expertise to advance their clinical pipeline.”

“CareDx is at the leading edge of transplant innovation and has been instrumental in driving paradigm shifts in clinical practice through their non-invasive testing services which are widely used by leading organ transplant centers across the U.S.,” said Jeff Ross Ph.D., CEO of Miromatrix. “Our partnership with CareDx allows us to tap into their expertise in ways that may help us accelerate our momentum as we drive the next wave of innovation with bioengineered alternatives for use in human organ transplants.”

It is estimated that more than 100,000 people in the U.S. are waiting for an organ transplant,1 but only slightly more than half of them are expected to receive an organ within five years.2 It is estimated that 17 people die each day waiting for an organ transplant.1

About CareDx – The Transplant Company

CareDx, Inc., headquartered in Brisbane, California, is a leading precision medicine solutions company focused on the discovery, development, and commercialization of clinically differentiated, high-value healthcare solutions for transplant patients and caregivers. CareDx offers testing services, products, and digital healthcare solutions along the pre- and post-transplant patient journey and is the leading provider of genomics-based information for transplant patients. For more information, please visit: caredx.com.

About Miromatrix

Miromatrix Medical Inc. is a life sciences company pioneering a novel technology for bioengineering fully transplantable human organs to help save and improve patients' lives. Miromatrix has developed a proprietary perfusion technology platform for bioengineering organs that it believes will efficiently scale to address the shortage of available human organs. Miromatrix’s initial development focus is on human livers and kidneys. For more information, visit: miromatrix.com.